… Progress in both areas should advance preclinical assays of novel therapeutics. In that
regard, more progress in establishing patient-derived spheroid, organoid, and xenograft models …

… process may help to identify novel therapies to improve treatment outcomes. We present
a complementary bioinformatics approach to identify novel therapies for pNETs. A previous …

… , overexpress this marker (65) and gastrinomas of the pancreas show low expression …
pancreatic marker. Nuclear positivity for PR has been reported in most pancreatic endocrine tumors…

… be used to study liver metastasis and to test novel therapeutic strategies (74,75). The limitations
… Lastly, improving detection of aggressive tumors by evaluating novel molecular markers …

… An interesting recent work by Xue and colleagues carried out on 163 resected pancreatic
neuroendocrine tumors establishes the hepatoid variant as one of the most aggressive group …

… Though a number of therapeutics are currently approved for the treatment for patients with
… Herein we describe novel therapeutics being developed for the treatment of advanced well-…

… Recent updates separate pancreatic neuroendocrine tumors into 2 broad … pancreatic
neuroendocrine tumors (panNET) and poorly differentiated pancreatic neuroendocrine carcinoma (…

… neuroendocrine tumors defines PDGFRα as an active participant in tumorigenesis. This
should drive the development of novel therapies aimed at reducing tumor … different cancers will …

… In this sense, the improvement in the biological knowledge of resistance mechanisms to
antiangiogenics would be relevant for novel therapies development that may improve patients’ …

… tumors. Great progress has been achieved in drug therapy and the combination with local
… strategies for the management of neuroendocrine tumor associated with liver metastases. …